(1882) Virchow Arch. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Volume: 242 Issue: 3 pp. Antibiotics sensitivity test was carried out toward 10 antibiotics using discs diffusion method. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases. Unable to process the form. 6. A report of 11 cases and appraisal of antibiotic therapy. It is an important type of pneumonia because of its severity, high incidence of complications, and elevated mortality [1]. ADVERTISEMENT: Supporters see fewer/no ads. 61-year-old woman with a long-standing history of alcohol abuse presented with a sudden onset of cough, pleuritic chest pain, dyspnea, fever, and rigors. Continuous improvement of the lesion was found on follow-up chest X-rays. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). The presence of gram-negative rods in Gram-stained smears suggests Klebsiella; they maybe capsulated and non-sporing. Klebsiella pneumoniae, a gram-negative organism, is an emerging common cause of PLA, particularly in patients with poorly controlled diabetes mellitus and without any pre-existing liver disease. by Wenlie Xie and Huixuan Jia. The 70 isolates were taken from diverse clinical specimens. Klebsiella pneumoniae (K. pneumoniae) are bacteria that normally live in your intestines and feces. [12,17] Aspiration pneumonia should always be suspected if the infiltrates are present bilaterally in the dependent or posterior portions of the lungs. Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium.It appears as a mucoid lactose fermenter on MacConkey agar.. CHEST Journal. Volume: 260 Issue: 1 pp. These bacteria are harmless when they’re in … Klebsiella pneumoniae is a bacterium that normally lives inside human intestines, where it doesn't cause disease.. Okada F, Ando Y, Honda K et-al. Risk factors for Klebsiella pneumonia include alcoholism, diabetes mellitus, and COPD. Extensive right upper lobe consolidation, with bulging of the horizontal fissure. Pulmonary infection can also be classified into several radiologic and pathologic patterns according to its morphologic features. Hansell DM. 2010;83 (994): 854-60. Klebsiella is also responsible for a significant number of community-acquired infections. Gadkowski LB, Stout JE. Conversely, various pathogens give rise to identical radiologic findings; e.g., bronchopneumonia can be caused by, for example, Staphylococcus aureus, Klebsiella, Proteus, or Pseudomonas. Klebsiella species are a Gram-negative rod shaped bacteria belonging to the Enterobacteriaceae family. Check for errors and try again. Invasive community-acquired infections, including pyogenic liver abscesses, caused by hypervirulent Klebsiella pneumoniae (hvKp) strains have been well recognized worldwide. Recommended Articles. Lippincott Williams &Wilkins. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. In comparison, cavitation is rare in pneumococcal pneumonia. The past 3 decades have seen the emergence of an invasive liver abscess syndrome caused by Klebsiella pneumoniae that may manifest with metastatic infection to the eye, brain, or lung [1, 2]. The hypervirulence of these novel community-acquired strains is mediated in part by their hypermucoviscous phenotypes associated with K1 and K2 capsule serotypes [ 3–5 ]. Radiology 2007. Anat. Cavitary pulmonary disease. Diagnosis: Klebsiella pneumonia (aka Friedländer’s pneumonia) - Images, diagnosis, treatment options, review - Thoracic Imaging Case. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. This occurs early and progresses quickly. Friedlander, C. Über die Pseudomyceten bei der acuten fibrinösen Pneumoniae. 7. Klebsiella pneumonia usually results from aspiration of colonizing oropharyngeal microbes into the lower respiratory tract. Br J Radiol. Complications of Klebsiella pneumonia: CT evaluation. Klebsiella pneumoniae is a gram-negative, encapsulated, non-motile bacterium that is found in the environment and has been associated with pneumonia in the alcoholic and diabetic patient population. Figure Klebsiella pneumoniae liver abscess cases (n=123) in an outpatient parenteral antibiotic therapy (OPAT) cohort in Singapore, 2006–11 (n=2229) View Large Image Figure Viewer; Download Hi-res image Download (PPT) Roughly 70% of patients with K pneumoniae abscesses were men. J Comput Assist Tomogr. Klebsiella pneumoniae is a Gram-negative bacteria and a well-known cause of community-acquired pneumonia, which accounts for less than 5% of all cases of pneumonia. 4. (1968) Diseases of the chest. Klebsiella [kleb−see−ell−uh] is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis. Friedlander's pneumonia. Hansell DM. Among these, sporadic hvKp-related community-acquired pneumonia (CAP) is an acute-onset, rapidly progressing disease that can likely turn fatal, if left untreated. the Western countries, Klebsiella pneumoniae invasive syn-drome (KPIS) should be alerted when patients present atypi-cal vague symptoms including fever, chill, nausea, vomiting, and right upper quadrant tenderness. 2008;21 (2): 305-33, table of contents. There can b… (2009) ISBN:0723434964. Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae: US Appearance and Aspiration Findings. This occurs early and progresses quickly. There has been a considerable increase in the incidence of this type of pneumonia beginning in 1954 and reaching a peak in 1956, with 21 cases. 2. Necrotizing pneumonia can occur as a complication 6. There tends to be a higher prevalence in older patients with alcoholism and debilitated hospitalized patients 3. 3. K pneumoniae monomicrobial liver abscesses were associated with diabetes mellitus (P <.001), higher blood glucose levels at admission (P <.05), predominantly solid US appearances (P <.001), irregular or indistinct lesion margins (P <.05), less than 2 mL of pus aspirated (P <.001), and longer duration of antibiotic treatment (P <.05). Sputum analysis grew Klebsiella pneumoniae. 5. ; Material is inoculated into blood agar and Mac Conkey agar medium and incubated aerobically. All rights reserved. Since 1950, 76 proved cases of pneumonia due to Staphylococcus aureus have been seen at the Los Angeles County Hospital. 01 Jul 2011 Radiology. (2009) ISBN:0723434964. Chronic Klebsiella pneumonia: a rare manifestation of Klebsiella pneumonia. 8. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. Mosby Incorporated. 2011;140 (4_MeetingAbstracts): . In the setting of pneumonia, infection with K. pneumoniae is confirmed by either sputum culture analysis, blood culture analysis or midstream urine depending upon the illness. Authors S ... diagnostic radiology studies, therapeutic modalities and risk factors associated with mortality were studied. These infections are particularly a problem among neonates, elderly and immunocompromised individuals. The organism Klebsiella pneumoniae was first described by German microbiologist Carl Friedländer (1847-1887) in 1882, in a series of patients with Klebsiella pneumonia 7,8. It is not possible radiologically to pinpoint the causative organism. Klebsiella pneumonia is a necrotizing process with a predilection for debilitated people. {"url":"/signup-modal-props.json?lang=us\u0026email="}. (2007) ISBN:B0011ZYZR2. In nosocomial pneumonia, patchy bronchial pneumonia is the most common finding and is likely caused by Gram-negative pathogens, especially Pseudomonas or Klebsiella. Case of the Week: August 27-September 3, 2009. K. pneumoniae is also a well-known cause of community-acquired pneumonia. Nineteen cases were seen in the first half of 1958. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Chronic Klebsiella pneumonia was diagnosed and ceftazidime was changed to ceftriaxone 1 g every 12 h for 2 weeks. bulging of the horizontal fissure in this case) is less common nowadays with modern antibiotic treatment. Massive necrosis (pulmonary gangrene) is a recognized complication. The Brant and Helms Solution. Lobar expansion (e.g. Often there can be extensive lobar opacification with air bronchograms. Klebsiella pneumoniae renal abscess Zhonghua Yi Xue Za Zhi (Taipei). The spectrum includes. Unable to process the form. After that, a 6-week course of amoxicillin-clavulanate (1 g every 12 h) was substituted. Klebsiella spp. are commonly implicated as a cause of bacterial pneumonia in horses, but few reports describe the clinical presentation and progression of disease attributable to this organism. The disease is often overlooked in the Western physicians due to its rarity. On CXR, consolidation is lobar and resembles streptococcus pneumonia. Microbiol. Coronavirus: ... 2 Division of Diagnostic Radiology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. On CXR, consolidation is lobar and resembles streptococcus pneumonia. Acute Klebsiella pneumoniae pneumonia alone and with concurrent infection: comparison of clinical and thin-section CT findings. The bacterium typically colonizes human mucosal … Imaging of Diseases of the Chest. This organism can cause extensive pulmonary necrosis and frequent cavitation 1. 769-776. Klebsiella pneumoniae was first described by a German microbiologist and pathologist Carl Friedländer in 1882. Seventy of Klebsiella pneumoniae isolates had been collected from some Hospitals in Baghdad city from October to December 2017. 1 - 5 Although single case reports discuss the clinical presentation of pneumonia caused by Escherichia coli or Actinobacillus spp., 6, 7 to the authors’ knowledge no large retrospective studies describe the … 27-05-2014 - Klebsiella pneumonia is refers to a pneumonia resulting from an infection from the organism Klebsiella pneumoniae. They are commonly found in the environment and in … Klebsiella species cause a wide range of diseases including pneumonia, urinary tract infections (UTIs), bloodstream infections and sepsis. Introduction . 129-138. On CXR, consolidation is lobar and resembles streptococcus pneumonia. Klebsiella pneumoniae(K. pneumoniae) is a Gram-negative, non-motile, capsulated, gas-producing enteric bacillus widely found in nature, and it belongs to the normal flora of the human oral cavity and intestine. Clin. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). Mosby Incorporated. Radiology 2011. Massive necrosis (pulmonary gangrene) is a recognized complication. {"url":"/signup-modal-props.json?lang=us\u0026email="}. There can be variable features on chest HRCT which can also depend on current other organisms. Check for errors and try again. Klebsiella pneumoniae is a Gram-negative bacillus with worldwide distribution that usually causes respiratory and urinary tract infections, ... Four weeks after admission, following discussion with Radiology, a thoracic CT scan was performed for subsequent biopsy of one of the pulmonary lesions. All K. pneumoniae isolates were identified based on API 20 E and Vitek2 compact system. Results: The mean age was 58.7 years and the male to female ratio was 10:14. The three most common patterns are lobar pneumonia, bronchopneumonia, and interstitial pneumonia. 2000 Oct;63(10):721-8. CT Appearance of Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae. 53 (4): 481-6. Also, lobar expansion is not specific for Klebsiella infection. 1. Klebsiella pneumoniae is among the most common Gram-negative bacteria encountered by physicians worldwide and accounts for 0.5-5.0% of all cases of pneumonia 2. Moon WK, Im JG, Yeon KM et-al. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). K. pneumoniaewas first discovered by Friedlander in 1882 and considered to be responsible for a severe form of lobar pneumonia. Rev. Ono A. Less common forms of infection include cellular bronchiolitis, septic embolism, miliary infection, and lung abscess. Klebsiella pneumonia, also known as Friedländer pneumonia, refers to pneumonia resulting from an infection from the organism Klebsiella pneumoniae. 1995;19 (2): 176-81. The Post-operative Abdomen - Surgicel … Klebsiella pneumonia | Radiology Reference Article | Radiopaedia.org. It has a high mortality rate of approximately 50% even with antimicrobial therapy. WebMD does not provide medical advice, diagnosis or treatment. However, in general, the type of microorganism implicated in pneumonia can be identified (bacteria, viruses, or fungi). The chest films of 58 patients with proved pneumonia due to Pseudomonas, Klebsiella, Enterobacter, Escherichia coli, Proteus, or Bacteroides were reviewed.Pseudomonas pneumonia was characterized by diffuse alveolar involvement with rapid progression to extensive macrocavitation. This occurs early and progresses quickly. To retrospectively compare the computed tomographic (CT) features of liver abscesses caused by Klebsiella pneumoniae with those caused by other bacterial pathogens. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Often there can be extensive lobar opacification with air bronchograms. Massive necrosis (pulmonary gangrene) is a recognized complication. VCU Department of Radiology VCU Medical Center. 87: 319. Path. Klebsiella pneumoniae- Pathogenicity and Clinical Manifestations. 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